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In the Phase 2 study the highest arm continued upward toward higher maintenance targets, but the core principle held throughout: escalate only after the current step is tolerated , in roughly four-week increments

The bridge specifically targets the chronic weight management indication

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But, in fact, the increase over placebo did not reach statistical significance

The current experimental study was conducted in accordance with the National Institute of Health guidelines on the care and use of laboratory animals, and it was approved by the Institutional Animal Care and Use Committee (IACUC) of our institution (IACUC approval # 160/1999/CPCSEA)

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